Home Is it usual that genomic DNA extracted from paraffin-embedded tissue is degraded?

Genomic DNA Extracted From Paraffin-Embedded Tissue Is Usually Degraded. It Does Not Show As A Clear Strong Band Of About 20-30 Kb As We Usually See When Fresh Sample Is Used. It Is Because Genomic DNA In Paraffin-Embedded Tissue Unavoidably Suffers From Degradation When Sample Has Been Treated And Stored Over A Long Period. DNA In This Case Is Not Suitable For Southern Blotting And Restriction Analysis Due To The Smearing. However, It Is Applicable For PCR.